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On the involvement of cell volume regulation mechanisms in post-hypertonic lysis and slow-freezing injury of human erythrocytes and its broader cryobiological significance

2023-04-28

Abstract excerpt

<h4>ABSTRACT</h4> An effort is made to explain the salt loading of hypertonicity-treated human red blood cells (RBC) and their post-hypertonic lysis, which occurs upon resuspension to isotonic media. It is recognized that the salt loading is consistent with the regulatory volume increase response - a physiological response applied by cells to adapt to hypertonic conditions. It is therefore hypothesized that salt...

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Literature Corpus work
b211f3c9-f853-51c3-98c8-f5c3cef17195
DOI
10.1101/2023.04.28.538673
Open publication

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