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Article

From Traditional Biomarkers to Transcriptome Analysis in Drug Development

1 Feb 2005

Abstract excerpt

Traditional biomarkers have played an important role in drug development as well as patient care. A single traditional biomarker or surrogate endpoint is unlikely to either characterize the complete pathophysiology of a complex disease or capture all the therapeutic benefits or potential adverse effects that a drug will have in a diverse patient population. Transciptome analysis, on the other hand, can provide a...

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PMID: 15720268
DOI: 10.2174/1566524053152915

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