Article
A randomized, prospective study of phenotype susceptibility testing versus standard of care to manage antiretroviral therapy: CCTG 575.
AIDS (London, England) - 18 Feb 2005
Haubrich Richard H, Kemper Carol A, Hellmann Nicholas S, Keiser Philip H, Witt Mallory D, Tilles Jeremiah G, Forthal Donald N, Leedom John, Leibowitz Matthew, McCutchan J Allen, Richman Douglas D
Abstract excerpt
OBJECTIVE: To assess phenotype susceptibility testing (PHENO) with standard of care (SOC) to improve antiretroviral therapy. DESIGN: A prospective, multicenter study of 238 patients taking a stable antiretroviral regimen for > 6 months, with one or two protease inhibitors (PI) and entry HIV RNA > 400 copies/ml. METHOD: Patients were randomized to receive or not receive PHENO results for selecting antiretroviral...
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