Article
A randomized trial assessing the impact of phenotypic resistance testing on antiretroviral therapy.
AIDS (London, England) - 8 Mar 2002
Cohen Calvin J, Hunt Susan, Sension Michael, Farthing Charles, Conant Marcus, Jacobson Susan, Nadler Jeffrey, Verbiest Werner, Hertogs Kurt, Ames Michael, Rinehart Alex R, Graham Neil M
Abstract excerpt
OBJECTIVE: To compare the effect of treatment decisions guided by phenotypic resistance testing (PRT) or standard of care (SOC) on short-term virological response. DESIGN: A prospective, randomized, controlled clinical trial conducted in 25 university and private practice centers in the United States. PARTICIPANTS: A total of 272 subjects who failed to achieve or maintain virological suppression (HIV-1-RNA plasma...
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