Article
Genetic variation in the progesterone receptor gene and ovarian cancer risk.
American journal of epidemiology - 1 Mar 2005
Terry Kathryn L, De Vivo Immaculata, Titus-Ernstoff Linda, Sluss Patrick M, Cramer Daniel W
Abstract excerpt
Evidence suggests a role for progesterone in ovarian cancer development. Progesterone exerts its effect on target cells by interacting with its receptor. Thus, genetic variations that may cause alterations in the biologic functions of the progesterone receptor can potentially contribute to individual susceptibility to ovarian cancer. Using a population-based, case-control study, the authors genotyped four...
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