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Article

MnSOD genotype and prostate cancer risk as a function of NAT genotype and smoking status.

In vivo (Athens, Greece) - 1 Jan 2000

Iguchi Taro, Sugita Shozo, Wang Ching Y, Newman Nancy B, Nakatani Tatsuya, Haas Gabriel P

Abstract excerpt

BACKGROUND: Cigarette smoke contains carcinogenic aromatic and heterocyclic amines that are metabolized by N-acetyltransferase (NAT). These carcinogens also produce reactive oxygen species that are metabolized by manganese superoxide dismutase (MnSOD). The association between prostate cancer (PCA) and the polymorphism of MnSOD and NAT, and cigarette smoking was investigated. PATIENTS AND METHODS: DNA samples from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19368118
PMCID: PMC2670457

Genes

NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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