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Article

The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane.

Molecular biology of the cell - 1 May 2005

Ivetac Ivan, Munday Adam D, Kisseleva Marina V, Zhang Xiang-Ming, Luff Susan, Tiganis Tony, Whisstock James C, Rowe Tony, Majerus Phillip W, Mitchell Christina A

Abstract excerpt

Endosomal trafficking is regulated by the recruitment of effector proteins to phosphatidylinositol 3-phosphate [PtdIns(3)P] on early endosomes. At the plasma membrane, phosphatidylinositol-(3,4)-bisphosphate [PtdIns(3,4)P2] binds the pleckstrin homology (PH) domain-containing proteins Akt and TAP...

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Identifiers

PMID: 15716355
DOI: 10.1091/mbc.e04-09-0799
PMCID: PMC1087230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15716355-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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