Article
Adsorption of serum fetuin to hydroxylapatite does not contribute to osteoblast phenotype modifications.
Journal of biomedical materials research. Part A - 1 Apr 2005
Xie Jianwei, Baumann Melissa J, McCabe Laura R
Abstract excerpt
Osteoblasts exhibit enhanced differentiation and altered gene profiles when cultured on hydroxyapatite (HA) compared to plastic surfaces. To begin determining mechanisms for this response, we used proteomics to identify proteins predominantly found in osteoblasts on HA but not plastic surfaces. Two-dimensional gel electrophoresis and Western analyses indicate that fetuin is abundant in extracts from HA, but not...
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