Article
HNA-1a, HNA-1b and HNA-1c gene frequencies in Argentineans.
Tissue antigens - 1 May 2008
de La Vega Elena C D, Nogués N, Fernández Montoya A, Oyonarte S, Solis E, Muñiz-Díaz E
Abstract excerpt
Human neutrophil antigens (HNA) are polymorphic structures located in the neutrophil membrane. The neutrophil-specific antigens HNA-1a (NA1), 1b (NA2) and 1c (SH) are well-recognized allotypic forms of FcgammaRIIIb and the most frequent targets of neutrophil alloantibodies. The aim of this study was to determine the gene frequencies of the neutrophil-specific antigens belonging to the HNA-1 system in blood donors...
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