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Article

Nuclear and mitochondrial localization signals overlap within bovine herpesvirus 1 tegument protein VP22.

The Journal of biological chemistry - 22 Apr 2005

Zhu Jun, Qiu Zhaohua, Wiese Christiane, Ishii Yohei, Friedrichsen Jen, Rajashekara Gireesh, Splitter Gary A

Abstract excerpt

VP22, a tegument protein of bovine herpesvirus 1, accumulates in the nucleus of infected and transiently transfected cells. Previous studies indicated a possible regulatory function of VP22 within nuclei, but how VP22 enters nuclei is unknown. Despite the abundance of basic residues within this protein, no classic nuclear localization signal (NLS) motif has been identified. To identify the signal directing...

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PMID: 15705574
DOI: 10.1074/jbc.M500054200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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