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Article

Gender-specific association of the SLC6A4 and DRD2 gene variants in bipolar disorder.

The international journal of neuropsychopharmacology - 1 Feb 2014

Wang Tzu-Yun, Lee Sheng-Yu, Chen Shiou-Lan, Chang Yun-Hsuan, Chen Shih-Heng, Huang San-Yuan, Tzeng Nian-Sheng, Wang Chen-Lin, Yeh Pin-Hsi, Chen Kao Chin, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band

Abstract excerpt

Findings on the association between the risk for developing bipolar disorder and the functions of the serotonin transporter-linked polymorphic region gene (5-HTTLPR) and dopamine D2 receptor gene (DRD2) variants are contradictory. One explanation for this is that a gender difference may exist for genetic contributions. We compared the gender-related main effects and the gene-to-gene interaction between serotonin...

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Identifiers

PMID: 24229495
DOI: 10.1017/S1461145713001296

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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