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Article

Linkage disequilibrium between dopamine D1 receptor gene (DRD1) and bipolar disorder.

Biological psychiatry - 15 Dec 2002

Ni Xingqun, Trakalo Joseph M, Mundo Emanuela, Macciardi Fabio M, Parikh Sagar, Lee Lisa, Kennedy James L

Abstract excerpt

BACKGROUND: Based on the dopamine hypothesis, the dopamine D1 receptor gene (DRD1) is considered to be a good candidate gene for bipolar disorder (BP). METHODS: In our study, three polymorphisms of the DRD1 gene, -800T/C, -48A/G, and 1403T/C, were analyzed in 286 BP trios. Both the transmission disequilibrium test (TDT) and haplotype TDT were performed on the genotype data to test for the presence of linkage...

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Source

Identifiers

PMID: 12488059
DOI: 10.1016/s0006-3223(02)01433-6

Genes

DRD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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