Article
Mucinous carcinomas of the colorectum have distinct molecular genetic characteristics.
International journal of oncology - 1 Mar 2005
Song Geun Am, Deng Guoren, Bell Ian, Kakar Sanjay, Sleisenger Marvin H, Kim Young S
Abstract excerpt
We compared the frequency of CpG island methylation phenotype (CIMP), inactivation of APC, p53 and DCC genes and K-ras and BRAF mutations in 39 mucinous carcinomas (MC) and 34 non-mucinous carcinomas (NMC) of the colorectum with different microsatellite instability (MSI) status. The higher incidence of MSI (36% vs. 18%) was observed in MC compared with NMC. APC inactivation and K-ras mutations occurred more...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
