Article
[Glucokinase gene abnormalities in maturity-onset diabetes of the young (MODY) and late-onset NIDDM].
Nihon rinsho. Japanese journal of clinical medicine - 1 Oct 1994
Odawara M
Abstract excerpt
Glucokinase is a key enzyme of glucose metabolism that phosphorylates glucose to glucose-6-phosphate (G-6-P). This is the first step of glucose metabolism after the uptake of glucose by glucose transporter 2 (GLUT 2). Glucokinase is one of the hexo-kinases and is expressed only in pancreatic beta cells and hepatocytes. Recently it was reported that glucokinase gene is associated with some families with MODY...
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