Article
[Glucokinase gene abnormalities in maturity-onset diabetes of the young (MODY) and late-onset NIDDM].
Nihon rinsho. Japanese journal of clinical medicine - 1 Oct 1994
Odawara M
Abstract excerpt
Glucokinase is a key enzyme of glucose metabolism that phosphorylates glucose to glucose-6-phosphate (G-6-P). This is the first step of glucose metabolism after the uptake of glucose by glucose transporter 2 (GLUT 2). Glucokinase is one of the hexo-kinases and is expressed only in pancreatic beta...
Topics
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Female
- Glucokinase
- Humans
- Male
- Mutation
- Pedigree
