Article
MICA gene polymorphism in HBDI multiplex families.
Annals of the New York Academy of Sciences - 1 Dec 2004
Nikitina-Zake Liene, Ghaderi Mehran, Park Yongsoo, Babu Sunanda, Eisenbarth George, Sanjeevi Carani B
Abstract excerpt
T1DM is a disease that affects pancreatic beta cells and results in severe insulin depletion. T1DM is a multigenic disease, and the strongest genetic association with this disease is shown by the genes in MHC class II, namely, DQA1 and DQB1. The other gene that has been implicated in susceptibility to T1DM is the MICA gene that lies within the MHC class I region. This gene has been investigated in many autoimmune...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
