Article
An Angiopoietin-2 gene polymorphism in unexplained intrauterine fetal death: a multi-center study.
Journal of reproductive immunology - 1 Feb 2005
Huber Ambros, Grimm Christoph, Pietrowski Detlef, Zeillinger Robert, Bettendorf Hertha, Husslein Peter, Hefler Lukas
Abstract excerpt
OBJECTIVE: Angiopoietin-2 (Ang-2) is a potent regulator of angiogenesis and vascular tone. As vascular processes have been proposed to be involved in the pathogenesis of pregnancy associated complications such as late unexplained intrauterine fetal death (IUFD), we determined whether a common G/A polymorphism of the Ang-2 gene (ANGPT2) is associated with this condition. METHODS: In a multicenter case-control...
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