Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No associations between Parkinson's disease and polymorphisms of the quinone oxidoreductase (NQO1, NQO2) genes.

Neuroscience letters - 3 Mar 2005

Okada Starlyn, Farin Federico M, Stapleton Patricia, Viernes Hanna, Quigley Sean D, Powers Karen M, Smith-Weller Terri, Franklin Gary M, Longstreth W T, Swanson Phillip D, Checkoway Harvey

Abstract excerpt

Reactive oxygen species derived from dopamine metabolism can induce oxidative stress and thus may contribute to Parkinson's disease (PD) pathogenesis. The quinone oxidoreductases, nicotinamide adenine dinucleotide (phosphate) (NAD[P]H): quinone oxidoreductase 1 (NQO1) and dihydronicotinamide riboside (NRH): quinone oxidoreductase 2 (NQO2) detoxify quinones and quinonoid compounds. We investigated associations of...

Topics

Aged
Alleles
Case-Control Studies
Confidence Intervals
Female
Genotype
Humans
Male
Molecular Sequence Data
NAD(P)H Dehydrogenase (Quinone)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Odds Ratio

Parkinson Disease

Polymorphism, Genetic

Quinone Reductases

Source

Identifiers

PMID: 15694256
DOI: 10.1016/j.neulet.2004.11.009

Genes

NQO1
NQO2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15694256-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No associations between Parkinson's disease and polymorphisms of the quinone oxidoreductase (NQO1, NQO2) genes.PMID 15694256Read ↗

An association between idiopathic Parkinson's disease and polymorphisms of phase II detoxification enzymes: glutathione S-transferase M1 and quinone oxidoreductase 1 and 2.Semantic proximity Read ↗

Association of NRH:quinone oxidoreductase 2 gene promoter polymorphism with higher gene expression and increased susceptibility to Parkinson's disease.Semantic proximity Read ↗

Genetic polymorphisms of superoxide dismutase in Parkinson's disease.Semantic proximity Read ↗

Association of Polymorphism of Neuronal Nitric Oxide Synthase Gene with Risk to Parkinson's Disease.Semantic proximity Read ↗

No association between Parkinson's disease and monoamine oxidase A and B gene polymorphisms.Semantic proximity Read ↗

[A study on the relationship between polymorphism of human NAD(P)H: quinone oxidoreductase and Parkinson's disease in Chinese].Semantic proximity Read ↗

Superoxide dismutase coding of gene polymorphisms associated with susceptibility to Parkinson’s diseaseSemantic proximity Read ↗

Case-control study of debrisoquine 4-hydroxylase, N-acetyltransferase 2, and apolipoprotein E gene polymorphisms in Parkinson's disease.Semantic proximity Read ↗

No association between paraoxonase 1 (PON1) gene polymorphisms and susceptibility to Parkinson's disease in a Chinese population.Semantic proximity Read ↗

Lack of association between cytochrome P450 2E1 gene polymorphisms and Parkinson's disease in a Chinese population.Semantic proximity Read ↗

No association of four candidate genetic variants in MnSOD and SYNIII with Parkinson's disease in two Chinese populations.Semantic proximity Read ↗

Comprehensive association analysis of the NOS2A gene with Parkinson disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.