Inhibition of neural crest cell differentiation by embryo ectodermal extract.

Abstract excerpt

The white mutation in Mexican axolotls has long been thought to be a defect associated with the embryonic extracellular environment, but not with embryonic neural crest cells. Thus it was believed that pigment cells in white axolotls disappear from the skin during early development, not because they are intrinsically defective but because they have no choice but to move into an unfavorable environment. We present...

Topics

• Ambystoma mexicanum
• Animals
• Cell Differentiation
• Culture Media, Serum-Free
• Culture Techniques
• Ectoderm
• Embryonic Induction
• Filtration
• Melanins
• Melanocyte-Stimulating Hormones
• Mutation