Article
CD69, an early activation antigen on lymphocytes, is constitutively expressed by human epidermal Langerhans cells.
The Journal of investigative dermatology - 1 May 1992
Bieber T, Rieger A, Stingl G, Sander E, Wanek P, Strobel I
Abstract excerpt
When screening skin cryosections with a panel of monoclonal antibodies (MoAb), we found that the anti-CD69 MoAb Leu-23 reacted with a subpopulation of epidermal dendritic cells, presumably Langerhans cells (LC). The staining intensity was enhanced by gentle trypsin pretreatment of the sections. Flow cytometric analysis of LC-enriched epidermal cells (EC) revealed that nearly all CD1a-bearing LC display anti-CD69...
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