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Article

Gene-gene and gene-environment interactions in mild hyperhomocysteinemia.

Pathophysiology of haemostasis and thrombosis - 1 Jan 2000

D'Angelo Armando, Mazzola Giuseppina, Fermo Isabella

Abstract excerpt

Mild/moderate hyperhomocysteinemia (HHcy), a highly prevalent condition, is independently associated with an increased risk of arterial and venous thromboembolic diseases. Early reports of the association of mild/moderate HHcy with juvenile venous thromboembolism have shown familiarity for HHcy in relatives of index cases with thrombosis. Similar to inherited thrombophilia defects, inheritance of the HHcy...

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Identifiers

PMID: 15692239
DOI: 10.1159/000083824

Genes

MTHFR
CBS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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