Article
Hyperhomocysteinemia as a risk factor for venous thrombosis.
Clinical chemistry and laboratory medicine - 1 Aug 2001
den Heijer M, Keijzer M B
Abstract excerpt
Classical homocystinuria is associated with arterial vascular diseases and venous thrombosis. In the last decade, several studies have been published indicating that even mild hyperhomocysteinemia is a risk factor for venous thrombosis. The 677C-->T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is an important cause of mild hyperhomocysteinemia, but this polymorphism does not seem to be a risk...
Topics
- Case-Control Studies
- Factor V
- Humans
- Hyperhomocysteinemia
- Methylenetetrahydrofolate Reductase (NADPH2)
- Mutation
- Odds Ratio
- Oxidoreductases Acting on CH-NH Group Donors
- Risk Factors
- Vascular Diseases
- Venous Thrombosis