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Article

Interaction between hyperhomocysteinemia and inherited thrombophilic factors in venous thromboembolism.

Seminars in thrombosis and hemostasis - 1 Jan 2000

De Stefano V, Casorelli I, Rossi E, Zappacosta B, Leone G

Abstract excerpt

Hyperhomocysteinemia is an established risk factor for deep vein thrombosis. Factor V Leiden has been reported to potentiate the thrombotic risk related with severe hyperhomocysteinemia, being more represented in thrombotic patients with homocystinuria as compared with patients without a history of thrombosis. The results concerning the interaction between moderate hyperhomocysteinemia and inherited thrombophilic...

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Source

Identifiers

PMID: 11011848
DOI: 10.1055/s-2000-8473

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction between hyperhomocysteinemia and inherited thrombophilic factors in venous thromboembolism.PMID 11011848Read ↗

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Hyperhomocysteinemia: no longer a consideration in the management of venous thromboembolism.Semantic proximity Read ↗

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Interaction Between Hyperhomocysteinemia, Mutated Methylenetetrahydrofolatereductase (MTHFR) and Inherited Thrombophilic Factors in Recurrent Venous ThrombosisSemantic proximity Read ↗

Role of polymorphisms in factor V (FV Leiden), prothrombin, plasminogen activator inhibitor type-1 (PAI-1), methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) genes as risk factors for thrombophilias.Semantic proximity Read ↗

Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients.Semantic proximity Read ↗

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