Article
Nitric oxide signalling and cellular adaptations to changes in oxygenation.
Toxicology - 15 Mar 2005
Postovit Lynne-Marie, Sullivan Richard, Adams Michael A, Graham Charles H
Abstract excerpt
Fluctuations in oxygen (O2) levels characterise the cellular microenvironment in physiological and pathological processes such as placentation and malignant progression. Cells adapt to such changes in oxygenation by modifying gene expression, thereby regulating a spectrum of functions. Recent studies indicate that an important mechanism by which cells adapt to changes in oxygenation involves modifications in...
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