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Article

Oxygen as a regulator of cellular phenotypes in pregnancy and cancer.

Canadian journal of physiology and pharmacology - 1 Feb 2002

Lash Gendie E, Postovit Lynne-Marie, Matthews Nicola E, Chung Eugene Y, Canning Matthew T, Pross Hugh, Adams Michael A, Graham Charles H

Abstract excerpt

Cellular phenotype is determined by genetic and microenvironmental factors. There is evidence that tissue oxygenation status is one of the microenvironmental factors regulating cellular behaviour. Both normal and pathological processes such as blastocyst implantation in the uterus, placentation, and rapidly growing tumours occur under conditions characterized by relatively low oxygen levels. In this review, we...

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PMID: 11934252
DOI: 10.1139/y02-008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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