Article
The role of the first growth factor domain of human factor IXa in binding to platelets and in factor X activation.
The Journal of biological chemistry - 25 Apr 1992
Ahmad S S, Rawala-Sheikh R, Cheung W F, Stafford D W, Walsh P N
Abstract excerpt
We have recently shown that thrombin-stimulated human platelets have specific, saturable receptors for factor IXa, occupancy of which promotes factor X activation (Ahmad, S. S., Rawala-Sheikh, R., and Walsh, P.N. (1989) J. Biol. Chem. 264, 3244-3251, 20012-20016; Rawala-Sheikh, R., Ahmad, S. S.,...
Topics
- Autoradiography
- Binding, Competitive
- Blood Platelets
- Epidermal Growth Factor
- Factor IXa
- Factor X
- Humans
- Kinetics
- Mutation
- Platelet Activation
- Recombinant Proteins
- Substrate Specificity
- Thrombin
