Article
Cancer risk to the gastric corpus in Japanese, its correlation with interleukin-1beta gene polymorphism (+3953*T) and Epstein-Barr virus infection.
International journal of cancer - 20 May 2005
Sakuma Kazuya, Uozaki Hiroshi, Chong Ja-Mun, Hironaka Mitsugu, Sudo Makoto, Ushiku Tetsuo, Nagai Hideo, Fukayama Masashi
Abstract excerpt
Polymorphisms of interleukin-1 (IL-1) genes have been reported to modify the risk of gastric carcinoma (GC) in Caucasians. The significance of IL-1beta gene polymorphisms was evaluated in Japanese GC patients with or without infection of Helicobacter pylori and Epstein Barr virus (EBV) with special reference to the topographic features of GC. IL-1beta gene polymorphisms at positions -511 and +3953 were evaluated...
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