Article
Fifty years of cytogenetics: a parallel view of the evolution of cytogenetics and genotoxicology.
Biochimica et biophysica acta - 1 Jan 2000
Garcia-Sagredo J M
Abstract excerpt
A parallelism exists between human cytogenetics and cytogenetic toxicology. The breakthroughs, mostly coming from and used in clinical genetics, are widely used in genetic toxicology. The birth of human cytogenetics occurred in 1956 when it was published that the diploid number of chromosomes in humans is 46. The first stage in chromosome-induced mutagenesis began in 1938 when Sax published the effects of X-rays...
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