Article
Harderian gland hyperplasia in c-mos transgenic mice.
International journal of cancer - 8 May 1992
Heath L A, Rosenberg M P, Thorogood P, Speight P, Propst F
Abstract excerpt
Transgenic mice carrying the mouse mos proto-oncogene linked to a retroviral LTR develop hyperplasia of the Harderian glands. Enlargement of the glands is evident as early as 18 weeks after birth, with glands reaching up to 10 times their normal weight. Approximately 65% of the cases of hyperplasia occur bilaterally, and the majority of mice affected are male (66%). Elevated levels of mos expression are found in...
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