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Article

Fibroblasts Can Be Genetically Modified to Produce Excitable Cells Capable of Electrical Coupling

1 Feb 2005

Abstract excerpt

BACKGROUND: Cardiac conduction occurs in an electrical syncytium of excitable cells connected by gap junctions. Disruption of these electrophysiological properties causes conduction slowing or block. Depending on the location of affected cells within the heart, this has the potential to result in clinical syndromes such as atrioventricular block. With a view to developing gene therapy strategies for repairing...

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PMID: 15687125
DOI: 10.1161/01.cir.0000153812.64956.ef

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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