Article
Expression of mitochondrial genes and transcription estimation in different brain areas in Alzheimer's disease patients.
Neurobiology of disease - 1 Mar 2005
Rodríguez-Santiago Benjamín, Nunes Virginia
Abstract excerpt
Accumulation of mitochondrial defects is hypothesised to play a role in the complex pathophysiology of the sporadic form of Alzheimer's disease (SAD). Changes in expression of mtDNA encoded genes have been reported in SAD. However no conclusive results were obtained by using different methodologies and analysing distinct transcripts in a variety of brain areas. Here, we measured the expression of five...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
