Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial genes are altered in blood early in Alzheimer's disease

7 Jan 2017

Abstract excerpt

Although mitochondrial dysfunction is a consistent feature of Alzheimer's disease in the brain and blood, the molecular mechanisms behind these phenomena are unknown. Here we have replicated our previous findings demonstrating reduced expression of nuclear-encoded oxidative phosphorylation (OXPHOS) subunits and subunits required for the translation of mitochondrial-encoded OXPHOS genes in blood from people with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Metabolism and Genetic Disorders
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28208064
DOI: 10.1016/j.neurobiolaging.2016.12.029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial genes are altered in blood early in Alzheimer's diseasePMID 28208064Read ↗

Mitochondrial DNA abundance in blood is associated with Alzheimer’s disease- and dementia-riskSemantic proximity Read ↗

Transcriptional Coordination between Mitochondrial and Nuclear Genomes for Oxidative Phosphorylation Is Disrupted in Alzheimer’s BrainSemantic proximity Read ↗

Altered Transcriptional Profile of Mitochondrial DNA-Encoded OXPHOS Subunits, Mitochondria Quality Control Genes, and Intracellular ATP Levels in Blood Samples of Patients with Parkinson’s DiseaseSemantic proximity Read ↗

The Role of Mitochondrial genome abundance in Alzheimer’s DiseaseSemantic proximity Read ↗

Decreased expression of nuclear and mitochondrial DNA-encoded genes of oxidative phosphorylation in association neocortex in Alzheimer diseaseSemantic proximity Read ↗

Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative diseaseSemantic proximity Read ↗

The role of mitochondrial genome abundance in Alzheimer's diseaseSemantic proximity Read ↗

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.Semantic proximity Read ↗

Mitochondrial DNA Copy Numbers in Pyramidal Neurons are Decreased and Mitochondrial Biogenesis Transcriptome Signaling is Disrupted in Alzheimer's Disease HippocampiSemantic proximity Read ↗

Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolitesSemantic proximity Read ↗

Is Mitochondria DNA Variation a Biomarker for AD?Semantic proximity Read ↗

The T9861C Mutation in the mtDNA-Encoded Cytochrome C Oxidase Subunit III Gene Occurs in High Frequency but with Unequal Distribution in the Alzheimer’s Disease BrainSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.