Article
Induction of smooth muscle cell-like phenotype in marrow-derived cells among regenerating urinary bladder smooth muscle cells.
The American journal of pathology - 1 Feb 2005
Kanematsu Akihiro, Yamamoto Shingo, Iwai-Kanai Eri, Kanatani Isao, Imamura Masaaki, Adam Rosalyn M, Tabata Yasuhiko, Ogawa Osamu
Abstract excerpt
Tissue regeneration on acellular matrix grafts has great potential for therapeutic organ reconstruction. However, hollow organs such as the bladder require smooth muscle cell regeneration, the mechanisms of which are not well defined. We investigated the mechanisms by which bone marrow cells participate in smooth muscle formation during urinary bladder regeneration, using in vivo and in vitro model systems. In...
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