Article
Phenotypic heterogeneity in multiple myeloma families.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Feb 2005
Lynch Henry T, Watson Patrice, Tarantolo Stefano, Wiernik Peter H, Quinn-Laquer Brigid, Isgur Bergsagel Karin, Huiart Laetitia, Olopade O I, Sobol Hagay, Sanger Warren, Hogg David, Weisenburger Dennis
Abstract excerpt
PURPOSE: To describe a series of families with familial multiple myeloma (MM). Observations were used to generate hypotheses about the role of genetic factors, the mode of inheritance of these factors, and the association of other cancers with familial MM. PATIENTS AND METHODS: This observational study consisted of 39 families with multiple cases of MM or related disorders from four collaborating research...
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