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Article

Familial monoclonal gammopathy of undetermined significance and multiple myeloma: epidemiology, risk factors, and biological characteristics.

Blood - 7 Jun 2012

Greenberg Alexandra J, Rajkumar S Vincent, Vachon Celine M

Abstract excerpt

Monoclonal gammopathy of undetermined significance (MGUS), a precursor to multiple myeloma (MM), is one of the most common premalignant conditions in the general population. The cause of MGUS is largely unknown. Recent studies show that there is an increased prevalence of MGUS in blood relatives of persons with lymphoproliferative and plasma cell proliferative disorders, suggesting presence of shared underlying...

Topics

Genetic Predisposition to Disease
Hematologic Neoplasms
Humans
Monoclonal Gammopathy of Undetermined Significance
Multiple Myeloma
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22354002
DOI: 10.1182/blood-2011-11-387324
PMCID: PMC3369675

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