Familial multiple myeloma: a family study and review of the literature.

doi:10.1093/jnci/93.19.1479

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Article

Familial multiple myeloma: a family study and review of the literature.

Journal of the National Cancer Institute - 3 Oct 2001

Lynch H T, Sanger W G, Pirruccello S, Quinn-Laquer B, Weisenburger D D

Abstract excerpt

BACKGROUND: The etiology of multiple myeloma (MM) remains obscure, although reports of familial clustering have implicated both a host susceptibility factor and environmental effects. Here we describe the medical histories of members of a family prone to MM. METHODS: We developed a pedigree for an MM-prone family by using information obtained from a questionnaire. Protein immunoelectrophoresis of serum and urine...

Topics

Adenocarcinoma
Adult
Aged
Aged, 80 and over
Chromosome Aberrations
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 14
Female
Genetic Predisposition to Disease
Humans
In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Karyotyping

Male

Melanoma

Middle Aged

Multiple Myeloma

Myeloma Proteins

Paraproteinemias

Source

Open in PubMed

Identifiers

PMID: 11584064
DOI: 10.1093/jnci/93.19.1479

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