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Article

Antibody neutralization escape mediated by point mutations in the intracytoplasmic tail of human immunodeficiency virus type 1 gp41.

Journal of virology - 1 Feb 2005

Kalia Vandana, Sarkar Surojit, Gupta Phalguni, Montelaro Ronald C

Abstract excerpt

The persistence of human immunodeficiency virus type 1 (HIV-1) infection in the presence of robust host immunity has been associated in part with variation in viral envelope proteins leading to antigenic variation and escape from neutralizing antibodies. Previous studies of natural neutralization escape mutants have predominantly focused on gp120 and gp41 ectodomain sequence variations that alter antibody binding...

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Identifiers

PMID: 15681412
DOI: 10.1128/JVI.79.4.2097-2107.2005
PMCID: PMC546547

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Source receipt: pubmed, retrieved 7 Sept 2026.

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