Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD19 signalling improves the Epstein-Barr virus-induced immortalization of human B cell.

Cell proliferation - 1 Feb 2005

Hur D Y, Lee M H, Kim J W, Kim J-H, Shin Y K, Rho J K, Kwack K B, Lee W J, Han B G

Abstract excerpt

Epstein-Barr virus (EBV) infection in vitro immortalizes primary B cells and generates B lymphoblastoid cell lines (LCLs). These EBV-LCLs have been used for several purposes in immunological and genetic studies, but some trials involving these transformations fail for unknown reasons, and several EBV-LCLs do not grow in normal culture. In this study, we improved the immortalization method by CD19 and B-cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD19
Share to Cell Separation
Share to Cell Transformation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epstein-Barr Virus Nuclear Antigens

Share to Herpesvirus 4, Human

Share to Immunophenotyping

Share to Leukocytes, Mononuclear

Share to Viral Matrix Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 15679865
DOI: 10.1111/j.1365-2184.2005.00328.x
PMCID: PMC6496141

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD19 signalling improves the Epstein-Barr virus-induced immortalization of human B cell.PMID 15679865Read ↗

Conditional Immortalization of Human B Cells by CD40 LigationSemantic proximity Read ↗

The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfoldSemantic proximity Read ↗

LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cellsSemantic proximity Read ↗

Epstein-barr virus immortalization and latencySemantic proximity Read ↗

Steps Involved in Immortalization and Tumorigenesis in Human B-Lymphoblastoid Cell Lines Transformed by Epstein-Barr VirusSemantic proximity Read ↗

Exosomes Derived from Burkitt’s Lymphoma Cell Lines Induce Proliferation, Differentiation, and Class-Switch Recombination in B CellsSemantic proximity Read ↗

Lymphoblastoid cell line with B1 cell characteristics established from a chronic lymphocytic leukemia clone by in vitro EBV infectionSemantic proximity Read ↗

Generation of Epstein‐Barr Virus (EBV)–Immortalized B Cell LinesSemantic proximity Read ↗

An efficient method for the rapid establishment of Epstein‐Barr virus immortalization of human B lymphocytesSemantic proximity Read ↗

Molecular virology of Epstein–Barr virusSemantic proximity Read ↗

Immortalization of human lymphocytes by Epstein-Barr virus.Semantic proximity Read ↗

Mechanisms of B-Cell Oncogenesis Induced by Epstein-Barr VirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.