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Article

An efficient method for the rapid establishment of Epstein‐Barr virus immortalization of human B lymphocytes

1 Aug 2003

Abstract excerpt

Several methods have been developed for the immortalization of B lymphocytes by Epstein-Barr virus (EBV). We developed an efficient method which reduces the time from culture initiation to immortalization and cryopreservation. Two infections of EBV to lymphocytes, and the use of phorbol ester-induced EBV stock significantly improved immortalization efficiency and reduced the time between initiation and...

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PMID: 12950388
DOI: 10.1046/j.1365-2184.2003.00276.x

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