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Article

Induction of DNA damage and apoptosis in Saccharomyces cerevisiae by a yeast killer toxin.

Cellular microbiology - 1 Mar 2005

Klassen Roland, Meinhardt Friedhelm

Abstract excerpt

The cellular response of Saccharomyces cerevisiae to a linear plasmid encoded killer toxin from Pichia acaciae was analysed. As for the Kluyveromyces lactis zymocin, such toxin was recently shown to bind to the target cell's chitin and probably acts by facilitating the import of a toxin subunit. However, as distinct from zymocin, which arrests cells in G1, it provokes S-phase arrest and concomitant DNA damage...

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Identifiers

PMID: 15679842
DOI: 10.1111/j.1462-5822.2004.00469.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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