Article
Pharmacogenetics of inflammatory bowel disease.
Novartis Foundation symposium - 1 Jan 2004
Kelleher Dermot, Farrell Richard, McManus Ross
Abstract excerpt
Therapeutic outcome in inflammatory bowel disease has traditionally been related to disease activity. Recent data suggest that individual differences in drug disposition and metabolism, some of which are genetically determined, may play a significant role in the outcome of therapy for inflammatory diseases. Polymorphisms in the thiopurine methyl transferase gene (TPMT) are known to influence the outcome of...
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