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Pharmacogenetics and pharmacogenomics in rheumatology.

Immunologic research - 1 Jul 2013

Szekanecz Zoltán, Meskó Bertalan, Poliska Szilard, Váncsa Andrea, Szamosi Szilvia, Végh Edit, Simkovics Enikö, Laki Judit, Kurkó Júlia, Besenyei Timea, Mikecz Katalin, Glant Tibor T, Nagy László

Abstract excerpt

Pharmacogenetics and pharmacogenomics deal with possible associations of a single genetic polymorphism or those of multiple gene profiles with responses to drugs. In rheumatology, genes and gene signatures may be associated with altered efficacy and/or safety of anti-inflammatory drugs, disease-modifying antirheumatic drugs (DMARDs) and biologics. In brief, genes of cytochrome P450, other enzymes involved in drug...

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Identifiers

PMID: 23564183
DOI: 10.1007/s12026-013-8405-z
PMCID: PMC4139282

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