Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens.

doi:10.1002/em.20110

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Article

Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens.

Environmental and molecular mutagenesis - 1 Jan 2000

Nohmi Takehiko, Masumura Ken-ichi

Abstract excerpt

Cellular DNA is exposed to a variety of exogenous and endogenous mutagens. A complete understanding of the importance of different types of DNA damage requires knowledge of the specific molecular alterations induced by different types of agents in specific target tissues in vivo. The gpt delta transgenic mouse model provides the opportunity to characterize tissue-specific DNA alterations because small and large...

Topics

Animals
Base Sequence
Bone Marrow
Colon
DNA Damage
Epidermis
Imidazoles
Indoles
Liver
Mice
Mice, Transgenic
Mitomycin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Pyridines

Radiation, Ionizing

Sequence Deletion

Spleen

Source

Open in PubMed

Identifiers

PMID: 15668939
DOI: 10.1002/em.20110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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