Article
Polyphosphate kinase: a new colonization factor of Helicobacter pylori.
FEMS microbiology letters - 1 Feb 2005
Ayraud Sarah, Janvier Blandine, Labigne Agnès, Ecobichon Chantal, Burucoa Christophe, Fauchère Jean-Louis
Abstract excerpt
In order to elucidate the role of polyphosphate kinase (PPK) during the course of an infection by Helicobacter pylori, PPK deficient mutants were constructed using two genetic backgrounds: Hp141v and X47-2AL. The efficiencies of the parental strains and the derivative mutants at colonizing the gastric mucosa of mice were compared. When animals received the Hp141v and the X47-2AL parental strains, 100% of the mice...
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