Article
Modification in the ppk gene of Helicobacter pylori during single and multiple experimental murine infections.
Infection and immunity - 1 Apr 2003
Ayraud Sarah, Janvier Blandine, Salaun Laurence, Fauchère Jean-Louis
Abstract excerpt
The bacterial pathogen Helicobacter pylori is highly adapted to the human stomach, and a high level of polymorphism is observed among clinical isolates. This polymorphism may be the consequence of adaptive changes during colonization, making a strain better able to survive, to evade the immune system, and to provoke a chronic infection. To investigate the mechanisms involved in the acquisition of diversity in H....
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