Evidence that sensitivity to cyclosporine is influenced by the HLA-DR phenotype of kidney graft recipients.

doi:10.1097/00007890-199204000-00010

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Article

Evidence that sensitivity to cyclosporine is influenced by the HLA-DR phenotype of kidney graft recipients.

Transplantation - 1 Apr 1992

Zlabinger G J, Kudlacek S, Pohanka E, Franz M, Hamilton G, Rosenmayr A, Kovarik J

Abstract excerpt

Clinical as well as experimental studies have shown a great interindividual variability in the immunosuppressive efficacy of CsA. Evaluating previous in vitro findings of a correlation between sensitivity of alloresponsiveness to CsA and the HLA-DR phenotype CsA levels were compared in kidney tra...

Topics

Adult
Aged
Cyclosporine
HLA-DR Antigens
Haplotypes
Humans
Kidney Transplantation
Middle Aged
Phenotype

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