Article
Evidence that sensitivity to cyclosporine is influenced by the HLA-DR phenotype of kidney graft recipients.
Transplantation - 1 Apr 1992
Zlabinger G J, Kudlacek S, Pohanka E, Franz M, Hamilton G, Rosenmayr A, Kovarik J
Abstract excerpt
Clinical as well as experimental studies have shown a great interindividual variability in the immunosuppressive efficacy of CsA. Evaluating previous in vitro findings of a correlation between sensitivity of alloresponsiveness to CsA and the HLA-DR phenotype CsA levels were compared in kidney transplant recipients with and without rejections during the early posttransplant period and tested for a possible...
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