Article
Disparity in HLA-DR typing and mixed lymphocyte culture reactivity.
Annals of clinical and laboratory science - 1 Jan 2000
Smith R A, Belcher R
Abstract excerpt
Prospective HLA-DR matching has been shown to enhance renal graft survival. It has also been demonstrated that the major stimuli in the one-way mixed lymphocyte culture reaction (MLR) are the DR rather than DQ class II histocompatibility antigens. A two antigen DR match between the potential recipient and donor is usually associated with a negative MLR. The findings of two family studies are reported in which...
Topics
- Bone Marrow Transplantation
- Female
- Graft Survival
- HLA-D Antigens
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Kidney Transplantation
- Lymphocyte Culture Test, Mixed
- Male
- Phenotype