Article
Genetic determinants on rat chromosome 6 modulate variation in the hypercapnic ventilatory response using consomic strains.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 May 2005
Dwinell M R, Forster H V, Petersen J, Rider A, Kunert M P, Cowley A W, Jacob H J
Abstract excerpt
To understand the genetic basis of pathways involved in the control of breathing, a large scale, high-throughput study using chromosomal substitution strains of rats is underway. Eight new consomic rat stains (SS-2(BN), SS-4(BN), SS-6(BN), SS-7(BN), SS-8(BN), SS-11(BN), SS-12(BN), SS-14(BN), SS-Y(BN)), containing one homozygous BN/NHsdMcwi (BN) chromosome on a background of SS/JrHsdMcwi (SS), were created by...
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