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Article

Use of consomic rats for genomic insights into ventilator-associated lung injury.

American journal of physiology. Lung cellular and molecular physiology - 1 Aug 2007

Nonas Stephanie A, Moreno-Vinasco Liliana, Vinasco Liliana Moreno, Ma Shwu Fan, Jacobson Jeffrey R, Desai Ankit A, Dudek Steven M, Flores Carlos, Hassoun Paul M, Sam Lee, Ye Shui Q, Moitra Jaideep, Barnard Joe, Grigoryev Dmitry N, Lussier Yves A, Garcia Joe G N

Abstract excerpt

Increasing evidence supports the contribution of genetic influences on susceptibility/severity in acute lung injury (ALI), a devastating syndrome requiring mechanical ventilation with subsequent risk for ventilator-associated lung injury (VALI). To identify VALI candidate genes, we determined that Brown Norway (BN) and Dahl salt-sensitive (SS) rat strains were differentially sensitive to VALI (tidal volume of 20...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17468131
DOI: 10.1152/ajplung.00481.2006
PMCID: PMC3616407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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