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Article

Ca2+-dependent expression of the CIRCE regulon in Streptococcus pneumoniae.

Molecular microbiology - 1 Jan 2005

Kwon Hyog-Young, Kim Su-Nam, Pyo Suhk-Neung, Rhee Dong-Kwon

Abstract excerpt

DnaK and GroEL play a pivotal role in protein folding, and promote cell proliferation and survival. In Gram-positive and several Gram-negative bacteria, HrcA represses the transcription of dnaK and groE operons by binding to the highly conserved CIRCE (controlling inverted repeat of chaperone expression) operator sequence in the presence of GroEL. HrcA may respond to environmental stress and various other factors...

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Identifiers

PMID: 15659163
DOI: 10.1111/j.1365-2958.2004.04416.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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