Article
The GroE chaperonin machine is a major modulator of the CIRCE heat shock regulon of Bacillus subtilis.
The EMBO journal - 1 Aug 1997
Mogk A, Homuth G, Scholz C, Kim L, Schmid F X, Schumann W
Abstract excerpt
Class I heat-inducible genes in Bacillus subtilis consist of the heptacistronic dnaK and the bicistronic groE operon and form the CIRCE regulon. Both operons are negatively regulated at the level of transcription by the HrcA repressor interacting with its operator, the CIRCE element. Here, we dem...
Topics
- Bacillus subtilis
- Bacterial Proteins
- Chaperonin 10
- Chaperonin 60
- Chaperonins
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Genes, Bacterial
- HSP40 Heat-Shock Proteins
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Hot Temperature
- Molecular Chaperones
- Mutation
- Operon
- Regulon