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Article

The GroE chaperonin machine is a major modulator of the CIRCE heat shock regulon of Bacillus subtilis.

The EMBO journal - 1 Aug 1997

Mogk A, Homuth G, Scholz C, Kim L, Schmid F X, Schumann W

Abstract excerpt

Class I heat-inducible genes in Bacillus subtilis consist of the heptacistronic dnaK and the bicistronic groE operon and form the CIRCE regulon. Both operons are negatively regulated at the level of transcription by the HrcA repressor interacting with its operator, the CIRCE element. Here, we demonstrate that the DnaK chaperone machine is not involved in the regulation of HrcA and that the GroE chaperonin exerts...

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Identifiers

PMID: 9303302
DOI: 10.1093/emboj/16.15.4579
PMCID: PMC1170084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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